anonychia-microcephaly syndrome
Findings
No curated finding names anonychia-microcephaly syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Anonychia-microcephaly syndrome is a multiple congenital anomaly disorder characterized by anonychia congenita totalis and microcephaly, and normal intelligence along with some minor anomalies including single transverse palmar creases, fifth-finger clinodactyly and widely-spaced teeth.
Definition from the Mondo Disease Ontology (MONDO:0011795), read 2026-09-29. CC BY 4.0.
Features
8 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- AnonychiaHPOHP:0001798
- Very frequent (80% to 99% of cases)
- Aplastic/hypoplastic toenailHPOHP:0010624
- Very frequent (80% to 99% of cases)
- Abnormality of the dentitionHPOHP:0000164
- Frequent (30% to 79% of cases)
- Bilateral single transverse palmar creasesHPOHP:0007598
- Frequent (30% to 79% of cases)
- MicrocephalyHPOHP:0000252
- Frequent (30% to 79% of cases)
- Carious teethHPOHP:0000670
- Occasional (5% to 29% of cases)
- Clinodactyly of the 5th fingerHPOHP:0004209
- Occasional (5% to 29% of cases)
- Sloping foreheadHPOHP:0000340
- Occasional (5% to 29% of cases)
Where it sits
Other names
1 name
Resolves to: anonychia-microcephaly syndrome
- Also called
- Teebi-Kaurah syndrome