angioosteohypertrophic syndrome
MONDO:0007864Mondo
Findings
No curated finding names angioosteohypertrophic syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A congenital vascular bone syndrome (CVBS) characterized by the presence of a vascular malformation in a limb, mainly of the arteriovenous type, which results in overgrowth of the affected limb.
Definition from the Mondo Disease Ontology (MONDO:0007864), read 2026-09-29. CC BY 4.0.
Features
31 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal skeletal morphologyHPOHP:0011842
- Very frequent (80% to 99% of cases)
- HemangiomaHPOHP:0001028
- Very frequent (80% to 99% of cases)
- Lower limb asymmetryHPOHP:0100559
- Very frequent (80% to 99% of cases)
- Upper limb asymmetryHPOHP:0100560
- Very frequent (80% to 99% of cases)
- Venous insufficiencyHPOHP:0005293
- Very frequent (80% to 99% of cases)
- CellulitisHPOHP:0100658
- Frequent (30% to 79% of cases)
- Gastrointestinal hemorrhageHPOHP:0002239
- Frequent (30% to 79% of cases)
- Pulmonary embolismHPOHP:0002204
- Frequent (30% to 79% of cases)
- Tall statureHPOHP:0000098
- Frequent (30% to 79% of cases)
- Venous thrombosisHPOHP:0004936
- Frequent (30% to 79% of cases)
- Abnormal skull morphologyHPOHP:0000929
- Occasional (5% to 29% of cases)
- Abnormal tricuspid valve morphologyHPOHP:0001702
- Occasional (5% to 29% of cases)
Show the remaining 19
- Abnormality of the menstrual cycleHPOHP:0000140
- Occasional (5% to 29% of cases)
- Abnormality of the pulmonary arteryHPOHP:0004414
- Occasional (5% to 29% of cases)
- AscitesHPOHP:0001541
- Occasional (5% to 29% of cases)
- Atrial septal defectHPOHP:0001631
- Occasional (5% to 29% of cases)
- Congestive heart failureHPOHP:0001635
- Occasional (5% to 29% of cases)
- EdemaHPOHP:0000969
- Occasional (5% to 29% of cases)
Where it sits
Other names
9 names
Resolves to: angioosteohypertrophic syndrome
- Also called
- angioosteohypertrophy syndromehaemangiectatic hypertrophyKlippel Trenaunay syndromeKlippel-Trenaunay SyndromeKlippel-Trénaunay syndromeKlippel-Trenaunay-Weber syndromeKlippel-Trénaunay-Weber syndromeKlippel-Trenaunay-Weber syndrome, Isolated casesWeber-Klippel-Trenaunay