aneurysm of sinus of Valsalva
MONDO:0015197Mondo
Findings
No curated finding names aneurysm of sinus of Valsalva yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Sinus of Valsalva aneurysm (SVA) is a rare congenital heart malformation of one or more of the aortic sinuses, consisting of a dilation that when unruptured is usually asymptomatic but when ruptured presents with progressive exertional dyspnea, fatigue, chest pain and that can lead to congestive heart failure if left untreated.
Definition from the Mondo Disease Ontology (MONDO:0015197), read 2026-09-29. CC BY 4.0.
Features
11 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Dilatation of the sinus of ValsalvaHPOHP:0011645
- Obligate (100% of cases)
- Aortic regurgitationHPOHP:0001659
- Frequent (30% to 79% of cases)
- DyspneaHPOHP:0002094
- Frequent (30% to 79% of cases)
- Heart murmurHPOHP:0030148
- Frequent (30% to 79% of cases)
- Congestive heart failureHPOHP:0001635
- Occasional (5% to 29% of cases)
- CoughHPOHP:0012735
- Occasional (5% to 29% of cases)
- EdemaHPOHP:0000969
- Occasional (5% to 29% of cases)
- Bacterial endocarditisHPOHP:0006689
- Very rare (1% to 4% of cases)
- Chest painHPOHP:0100749
- Very rare (1% to 4% of cases)
- OliguriaHPOHP:0100520
- Very rare (1% to 4% of cases)
- StrokeHPOHP:0001297
- Very rare (1% to 4% of cases)