amyotrophic lateral sclerosis type 9
Findings
No curated finding names amyotrophic lateral sclerosis type 9 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any amyotrophic lateral sclerosis in which the cause of the disease is a mutation in the ANG gene.
Definition from the Mondo Disease Ontology (MONDO:0012753), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
HPO, annotations 2026-09-02
Features
3 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Distal amyotrophyHPOHP:0003693
- Distal muscle weaknessHPOHP:0002460
- SpasticityHPOHP:0001257
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- ANGHGNC:483
- Definitive · Ambry Genetics · Autosomal dominant · 2018
- Strong · Genomics England PanelApp · Autosomal dominant · 2021
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2021
- Limited · ClinGen · Autosomal dominant · 2022
Where it sits
Other names
4 names
Resolves to: amyotrophic lateral sclerosis type 9
- Also called
- ALS9amyotrophic lateral sclerosis 9amyotrophic lateral sclerosis caused by mutation in ANGANG amyotrophic lateral sclerosis