amyotrophic lateral sclerosis type 6
Findings
No curated finding names amyotrophic lateral sclerosis type 6 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any amyotrophic lateral sclerosis in which the cause of the disease is a mutation in the FUS gene.
Definition from the Mondo Disease Ontology (MONDO:0011951), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
HPO, annotations 2026-09-02
Features
1 feature
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Gait disturbanceHPOHP:0001288
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- FUSHGNC:4010
- Definitive · ClinGen · Autosomal dominant · 2021
- Strong · Genomics England PanelApp · Autosomal dominant · 2021
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2023
Where it sits
Other names
3 names
Resolves to: amyotrophic lateral sclerosis type 6
- Also called
- ALS6amyotrophic lateral sclerosis caused by mutation in FUSFUS amyotrophic lateral sclerosis