amoebiasis due to free-living amoebae
Findings
No curated finding names amoebiasis due to free-living amoebae yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Free-living amebae belonging to the genera Acanthamoeba, Balamuthia, Naegleria and Sappinia are important causes of disease in humans and animals. Naegleria fowleri produces an acute, and usually lethal, central nervous system (CNS) disease called primary amebic meningoencephalitis (PAM). Acanthamoeba spp. and Balamuthia mandrillaris are opportunistic free-living amebae capable of causing granulomatous amebic encephalitis (GAE) in individuals with compromised immune systems. Sappinia pedata has been implicated in a case of amebic encephalitis. Naegleria fowleri and Acanthamoeba spp., are commonly found in lakes, swimming pools, tap water, and heating and air conditioning units.
Definition from the Mondo Disease Ontology (MONDO:0019036), read 2026-09-29. CC BY 4.0.
Features
68 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal cerebrospinal fluid morphologyHPOHP:0002921
- Frequent (30% to 79% of cases)
- Atypical behaviorHPOHP:0000708
- Frequent (30% to 79% of cases)
- Brain imaging abnormalityHPOHP:0410263
- Frequent (30% to 79% of cases)
- CSF lymphocytic pleiocytosisHPOHP:0200149
- Frequent (30% to 79% of cases)
- FeverHPOHP:0001945
- Frequent (30% to 79% of cases)
- HeadacheHPOHP:0002315
- Frequent (30% to 79% of cases)
- Increased CSF protein concentration
Show the remaining 56
- VomitingHPOHP:0002013
- Frequent (30% to 79% of cases)
- Abducens palsyHPOHP:0006897
- Occasional (5% to 29% of cases)
- Abnormal basal ganglia morphologyHPOHP:0002134
- Occasional (5% to 29% of cases)
- Abnormal brainstem MRI signal intensityHPOHP:0012747
- Occasional (5% to 29% of cases)
- Abnormal cerebellum morphologyHPOHP:0001317
- Occasional (5% to 29% of cases)
- Abnormal cerebral cortex morphologyHPOHP:0002538
- Occasional (5% to 29% of cases)
Where it sits
- A kind of