aldosterone-producing adrenal cortex adenoma
MONDO:0016505Mondo
Findings
No curated finding names aldosterone-producing adrenal cortex adenoma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
An adenoma of the adrenal cortex that produces aldosterone. It may be associated with Conn syndrome. Clinical presentation includes hypertension, hypokalemia, and muscle weakness.
Definition from the Mondo Disease Ontology (MONDO:0016505), read 2026-09-29. CC BY 4.0.
Features
18 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- HypertensionHPOHP:0000822
- Obligate (100% of cases)
- Neoplasm of the adrenal glandHPOHP:0100631
- Obligate (100% of cases)
- Decreased circulating renin concentrationHPOHP:0003351
- Very frequent (80% to 99% of cases)
- Glucocortocoid-insensitive primary hyperaldosteronismHPOHP:0011740
- Very frequent (80% to 99% of cases)
- HypokalemiaHPOHP:0002900
- Very frequent (80% to 99% of cases)
- Increased circulating cortisol levelHPOHP:0003118
- Very frequent (80% to 99% of cases)
- Metabolic alkalosisHPOHP:0200114
- Very frequent (80% to 99% of cases)
- Muscle weaknessHPOHP:0001324
- Very frequent (80% to 99% of cases)
- Abnormal T-waveHPOHP:0005135
- Frequent (30% to 79% of cases)
- Increased urinary potassiumHPOHP:0003081
- Frequent (30% to 79% of cases)
- Muscle spasmHPOHP:0003394
- Frequent (30% to 79% of cases)
- NauseaHPOHP:0002018
- Frequent (30% to 79% of cases)
Show the remaining 6
- PalpitationsHPOHP:0001962
- Frequent (30% to 79% of cases)
- ParesthesiaHPOHP:0003401
- Frequent (30% to 79% of cases)
- EpistaxisHPOHP:0000421
- Occasional (5% to 29% of cases)
- HeadacheHPOHP:0002315
- Occasional (5% to 29% of cases)
- Intracranial hemorrhageHPOHP:0002170
- Occasional (5% to 29% of cases)
- TinnitusHPOHP:0000360
- Occasional (5% to 29% of cases)
Where it sits
Other names
6 names
Resolves to: aldosterone-producing adrenal cortex adenoma
- Also called
- aldosterone producing adrenal cortex adenomaaldosterone producing adrenal cortical adenomaAPACPure aldosterone-producing adrenocortical carcinomaPure aldosterone-secreting adrenocortical carcinomaPure APAC