advanced sleep phase syndrome 1
MONDO:0011442Mondo
Findings
No curated finding names advanced sleep phase syndrome 1 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any advanced sleep phase syndrome in which the cause of the disease is a mutation in the PER2 gene.
Definition from the Mondo Disease Ontology (MONDO:0011442), read 2026-09-29. CC BY 4.0.
Features
1 feature
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Sleep-wake cycle disturbanceHPOHP:0006979
- Very frequent (80% to 99% of cases) · Juvenile onset
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- PER2HGNC:8846
- Limited · Labcorp Genetics (formerly Invitae) · Unknown · 2021
- Limited · PanelApp Australia · Autosomal dominant · 2025
Where it sits
- A kind of
Other names
5 names
Resolves to: advanced sleep phase syndrome 1
- Also called
- advanced sleep phase syndrome caused by mutation in PER2advanced sleep phase syndrome type 1advanced sleep phase syndrome, familial, type 1FASPS1PER2 advanced sleep phase syndrome