adiposis dolorosa
MONDO:0007070Mondo
Findings
No curated finding names adiposis dolorosa yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Adiposis dolorosa or Dercum's disease is characterized by the development of multiple, painful, subcutaneous lipomas in association with obesity, asthenia and fatigue, and range of mental disturbances including instability, depression, confusion, dementia and epilepsy.
Definition from the Mondo Disease Ontology (MONDO:0007070), read 2026-09-29. CC BY 4.0.
Features
39 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- AnxietyHPOHP:0000739
- Very frequent (80% to 99% of cases)
- ArthralgiaHPOHP:0002829
- Very frequent (80% to 99% of cases)
- DepressionHPOHP:0000716
- Very frequent (80% to 99% of cases)
- FatigueHPOHP:0012378
- Very frequent (80% to 99% of cases)
- ObesityHPOHP:0001513
- Very frequent (80% to 99% of cases)
- Subcutaneous noduleHPOHP:0001482
- Very frequent (80% to 99% of cases)
- Abdominal distentionHPOHP:0003270
- Frequent (30% to 79% of cases)
- Abdominal painHPOHP:0002027
- Frequent (30% to 79% of cases)
- Abnormal circulating lipid concentrationHPOHP:0003119
- Frequent (30% to 79% of cases)
- AstheniaHPOHP:0025406
- Frequent (30% to 79% of cases)
- Chronic painHPOHP:0012532
- Frequent (30% to 79% of cases)
- Elevated circulating C-reactive protein concentrationHPOHP:0011227
- Frequent (30% to 79% of cases)
Show the remaining 27
- Elevated erythrocyte sedimentation rateHPOHP:0003565
- Frequent (30% to 79% of cases)
- Increased total hemolytic complement activityHPOHP:0031905
- Frequent (30% to 79% of cases)
- OverweightHPOHP:0025502
- Frequent (30% to 79% of cases)
- Painful subcutaneous lipomasHPOHP:0007596
- Frequent (30% to 79% of cases)
- Sparse axillary hairHPOHP:0002215
- Frequent (30% to 79% of cases)
- Sparse pubic hairHPOHP:0002225
- Frequent (30% to 79% of cases)
Where it sits
Other names
6 names
Resolves to: adiposis dolorosa
- Also called
- Adiposalgiaadipose tissue rheumatismDercum diseaseDercum's Diseaselipomatosis dolorosaNeurolipomatosis