acute panmyelosis with myelofibrosis
MONDO:0019455Mondo
Findings
No curated finding names acute panmyelosis with myelofibrosis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
An acute myeloid leukemia characterized by bone marrow fibrosis without preexisting primary myelofibrosis.
Definition from the Mondo Disease Ontology (MONDO:0019455), read 2026-09-29. CC BY 4.0.
Features
15 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- MyelofibrosisHPOHP:0011974
- Very frequent (80% to 99% of cases)
- PancytopeniaHPOHP:0001876
- Very frequent (80% to 99% of cases)
- Abnormal megakaryocyte morphologyHPOHP:0012143
- Frequent (30% to 79% of cases)
- Abnormality of bone marrow stromal cellsHPOHP:0012129
- Frequent (30% to 79% of cases)
- Bone marrow hypercellularityHPOHP:0031020
- Frequent (30% to 79% of cases)
- FatigueHPOHP:0012378
- Frequent (30% to 79% of cases)
- Muscle weaknessHPOHP:0001324
- Frequent (30% to 79% of cases)
- Acute myeloid leukemiaHPOHP:0004808
- Occasional (5% to 29% of cases)
- Acute myelomonocytic leukemiaHPOHP:0004820
- Occasional (5% to 29% of cases)
- Bone marrow hypocellularityHPOHP:0005528
- Occasional (5% to 29% of cases)
- Increased micromegakaryocyte countHPOHP:0031386
- Occasional (5% to 29% of cases)
- Increased total lymphocyte countHPOHP:0100827
- Occasional (5% to 29% of cases)
Show the remaining 3
- Low back painHPOHP:0003419
- Occasional (5% to 29% of cases)
- Megakaryocyte nucleus hypolobulationHPOHP:0031385
- Occasional (5% to 29% of cases)
- SplenomegalyHPOHP:0001744
- Very rare (1% to 4% of cases)
Where it sits
Other names
7 names
Resolves to: acute panmyelosis with myelofibrosis
- Also called
- acute (malignant) myelofibrosisacute (malignant) myelosclerosisacute myelodysplasia with myelofibrosisacute myelofibrosisacute myelosclerosisacute panmyelosisAPMF