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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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PathwaysReactions grouped under one name
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DiseasesFeatures, genes, and where each sits

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Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

Disease

acute opioid poisoning

MONDO:0018173Mondo

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Findings

No curated finding names acute opioid poisoning yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.

Definition

Acute opioid poisoning is a rare intoxication with opioids, a large group of alkaloid analgesics, mainly characterized by miosis (pinpoint pupil), respiratory depression (bradypnea/apnea) and central nervous system depression (sedation or coma). Other manifestations include hypotension, reduced bowel motility, hypothermia and hypoglycemia. Naloxone, a competitive inhibitor of the mu-opioid receptor, is a potent antagonist and is used as the antidote for opioid intoxication.

Definition from the Mondo Disease Ontology (MONDO:0018173), read 2026-09-29. CC BY 4.0.

Where it sits

A kind of: acute disease
poisoning