acute lung injury
MONDO:0015796Mondo
Findings
No curated finding names acute lung injury yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A condition of lung damage that is characterized by bilateral pulmonary infiltrates (pulmonary edema) rich in neutrophils, and in the absence of clinical heart failure. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).
Definition from the Mondo Disease Ontology (MONDO:0015796), read 2026-09-29. CC BY 4.0.
Features
21 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal circulating cytokine concentrationHPOHP:0011112
- Frequent (30% to 79% of cases)
- DyspneaHPOHP:0002094
- Frequent (30% to 79% of cases)
- Elevated circulating C-reactive protein concentrationHPOHP:0011227
- Frequent (30% to 79% of cases)
- Elevated circulating surfactant protein concentrationHPOHP:0032094
- Frequent (30% to 79% of cases)
- HypoxemiaHPOHP:0012418
- Frequent (30% to 79% of cases)
- Increased circulating interleukin 6 concentrationHPOHP:0030783
- Frequent (30% to 79% of cases)
- PneumoniaHPOHP:0002090
- Frequent (30% to 79% of cases)
- Pulmonary infiltratesHPOHP:0002113
- Frequent (30% to 79% of cases)
- Respiratory distressHPOHP:0002098
- Frequent (30% to 79% of cases)
- Respiratory failureHPOHP:0002878
- Frequent (30% to 79% of cases)
- TachypneaHPOHP:0002789
- Frequent (30% to 79% of cases)
- Abnormal pulmonary interstitial morphologyHPOHP:0006530
- Occasional (5% to 29% of cases)
Show the remaining 9
- Abnormality of tumor necrosis factor secretionHPOHP:0011118
- Occasional (5% to 29% of cases)
- Acute pancreatitisHPOHP:0001735
- Occasional (5% to 29% of cases)
- Addictive alcohol useHPOHP:0030955
- Occasional (5% to 29% of cases)
- Diffuse alveolar hemorrhageHPOHP:0025420
- Occasional (5% to 29% of cases)
- EdemaHPOHP:0000969
- Occasional (5% to 29% of cases)
- FeverHPOHP:0001945
- Occasional (5% to 29% of cases)
Where it sits
- A kind of