acute disseminated encephalomyelitis
MONDO:0019383Mondo
Findings
No curated finding names acute disseminated encephalomyelitis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Acute disseminated encephalomyelitis (ADEM) is a demyelinating disorder of the central nervous system.
Definition from the Mondo Disease Ontology (MONDO:0019383), read 2026-09-29. CC BY 4.0.
Features
53 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- EncephalopathyHPOHP:0001298
- Obligate (100% of cases)
- CNS demyelinationHPOHP:0007305
- Very frequent (80% to 99% of cases)
- Diffuse white matter abnormalitiesHPOHP:0007204
- Very frequent (80% to 99% of cases)
- EEG with generalized slow activityHPOHP:0010845
- Very frequent (80% to 99% of cases)
- Abnormal basal ganglia morphologyHPOHP:0002134
- Frequent (30% to 79% of cases)
- Abnormal brainstem MRI signal intensityHPOHP:0012747
- Frequent (30% to 79% of cases)
- Abnormal cerebellum morphologyHPOHP:0001317
- Frequent (30% to 79% of cases)
- Abnormal periventricular white matter morphologyHPOHP:0002518
- Frequent (30% to 79% of cases)
- Abnormal pyramidal signHPOHP:0007256
- Frequent (30% to 79% of cases)
- Abnormal spinal cord morphologyHPOHP:0002143
- Frequent (30% to 79% of cases)
- Abnormal thalamic MRI signal intensityHPOHP:0012696
- Frequent (30% to 79% of cases)
- Anti-myelin oligodendrocyte glycoprotein antibody positivityHPOHP:0032492
- Frequent (30% to 79% of cases)
Show the remaining 41
- AtaxiaHPOHP:0001251
- Frequent (30% to 79% of cases)
- Atypical behaviorHPOHP:0000708
- Frequent (30% to 79% of cases)
- Cerebral edemaHPOHP:0002181
- Frequent (30% to 79% of cases)
- CSF lymphocytic pleiocytosisHPOHP:0200149
- Frequent (30% to 79% of cases)
- Disseminated viral infectionHPOHP:0031696
- Frequent (30% to 79% of cases)
- Excessive daytime somnolenceHPOHP:0001262
- Frequent (30% to 79% of cases)
Where it sits
Other names
3 names
Resolves to: acute disseminated encephalomyelitis
- Also called
- acute disseminated encephalitisADEMpost-infectious encephalomyelitis