acquired xanthinuria
MONDO:0021180Mondo
Findings
No curated finding names acquired xanthinuria yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Acquired xanthinuria is generally iatrogenic. Allopurinol treatment, administered to block XOR and prevent uric acid overproduction, leads to the accumulation of xanthine. Rarely, in the setting of aggressive chemotherapy with rapid tumor lysis or in patients with HPRT deficiency on allopurinol therapy, complications of renal failure can develop from xanthine crystal nephropathy.
Definition from the Mondo Disease Ontology (MONDO:0021180), read 2026-09-29. CC BY 4.0.