acquired partial lipodystrophy
MONDO:0012104Mondo
Findings
No curated finding names acquired partial lipodystrophy yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A lipodystrophy characterized by the association of lipoatrophy of the upper part of the body and lipohypertrophy of the thighs.
Definition from the Mondo Disease Ontology (MONDO:0012104), read 2026-09-29. CC BY 4.0.
Features
17 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- LipoatrophyHPOHP:0100578
- Very frequent (80% to 99% of cases)
- AutoimmunityHPOHP:0002960
- Frequent (30% to 79% of cases)
- Decreased circulating complement C3 concentrationHPOHP:0005421
- Frequent (30% to 79% of cases)
- Hearing impairmentHPOHP:0000365
- Frequent (30% to 79% of cases)
- Increased total lymphocyte countHPOHP:0100827
- Frequent (30% to 79% of cases)
- Intellectual disabilityHPOHP:0001249
- Frequent (30% to 79% of cases)
- MyopathyHPOHP:0003198
- Frequent (30% to 79% of cases)
- Progeroid facial appearanceHPOHP:0005328
- Frequent (30% to 79% of cases)
- SeizureHPOHP:0001250
- Frequent (30% to 79% of cases)
- ArthralgiaHPOHP:0002829
- Occasional (5% to 29% of cases)
- Generalized hirsutismHPOHP:0002230
- Occasional (5% to 29% of cases)
- GlomerulopathyHPOHP:0100820
- Occasional (5% to 29% of cases)
Show the remaining 5
- Hepatic steatosisHPOHP:0001397
- Occasional (5% to 29% of cases)
- ImmunodeficiencyHPOHP:0002721
- Occasional (5% to 29% of cases)
- Insulin resistanceHPOHP:0000855
- Occasional (5% to 29% of cases)
- Microscopic hematuriaHPOHP:0002907
- Occasional (5% to 29% of cases)
- ProteinuriaHPOHP:0000093
- Occasional (5% to 29% of cases)
Where it sits
Other names
4 names
Resolves to: acquired partial lipodystrophy
- Also called
- APLDBarraquer-Simons syndromepartial acquired lipodystrophyprogressive cephalothoracic lipodystrophy