5-fluorouracil poisoning
Findings
No curated finding names 5-fluorouracil poisoning yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
5-fluorouracil (5-FU) poisoning is a rare intoxication caused by the prolonged, low-dose administration of 5-FU, which is the mainstay of both adjuvant and advanced-disease chemotherapy regimens in colon cancer. 5-FU poisoning is characterized by gastrointestinal (nausea, emesis, diarrhea, anorexia, stomatitis) and hematologic (myelosuppression) toxicities as well as mucositis, alopecia and, occasionally, palmar-plantar dysesthesia (more commonly known as hand-foot syndrome). Women have been reported to experience more 5-FU-related toxicity than men.
Definition from the Mondo Disease Ontology (MONDO:0016312), read 2026-09-29. CC BY 4.0.
Where it sits
- A kind of
Other names
1 name
Resolves to: 5-fluorouracil poisoning
- Also called
- 5-fluorouracil intoxication