NCT02759107declared_contrast×6 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (Tirzepatide (Part A)=EXPERIMENTAL+subject, Placebo (Part A)=PLACEBO_COMPARATOR, Tirzepatide (Part B)=EXPERIMENTAL+subject, Placebo (Part B)=PLACEBO_COMPARATOR, Dulaglutide (Part B)=ACTIVE_COMPARATclinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT03131687declared_contrast×6, dose_stratum×6, verify:object_plausibility×4, commit×1 — "Change From Baseline in Body Weight" names CAT:outcome/prostate-volume ("Prostate volume") at least as well as CAT:outcome/body-mass ("Body mass") — the span does not pick out the endpoint claimedclinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT03311724declared_contrast×8 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (Placebo=PLACEBO_COMPARATOR, 4, 8 and 12mg Tirzepatide=unmatched, 2.5, 5, 10, and 15mg Tirzepatide=unmatched, 2.5, 7.5 and 15mg Tirzepatide=unmatched)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
Discarded — another reason, stated per paper7 papers
NCT03940742design×1 — allocation NON_RANDOMIZED -- not randomisedclinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT04172987design×1 — allocation NON_RANDOMIZED -- not randomisedclinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT04311424design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT04407234design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
Discarded — an endpoint this vocabulary does not hold1 paper
PMID:39814031no claim extracted — no_outcome_node — measured: incidence of any cancer (all-site cancer), RR from pooled randomised trials | incidence of any cancer (all sites combined), pooled risk ratio across RCTspipeline:batch2026-10-05
Discarded — the wrong intervention1 paper
NCT06640972intervention×1 — no declared intervention names tirzepatideclinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT03322631declared_contrast×4 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (Placebo=PLACEBO_COMPARATOR, 2.5 mg/5 mg/10 mg Tirzepatide (Cohort 1)=unmatched, 5 mg/10 mg/15 mg Tirzepatide (Cohort 2)=unmatched, 5 mg Tirzepatide (Cohort 3)=unmatched)
NCT03375463declared_contrast×4, arm_count×2 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (5 mg Tirzepatide SC (Lyophilized)-Part A=EXPERIMENTAL+subject, 5 mg Tirzepatide SC (Solution)-Part A=EXPERIMENTAL+subject)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT03482024declared_contrast×3 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (Tirzepatide - Control=EXPERIMENTAL+subject, Tirzepatide - Mild Renal Impairment=EXPERIMENTAL+subject, Tirzepatide - Moderate Renal Impairment=EXPERIMENTAL+subject, Tirzepatide - Severe Renal Impaiclinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT03730662declared_contrast×8 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (10 mg Tirzepatide=EXPERIMENTAL+subject, 15 mg Tirzepatide=EXPERIMENTAL+subject, Insulin Glargine=ACTIVE_COMPARATOR)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT03861039declared_contrast×13 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (5 mg Tirzepatide=EXPERIMENTAL+subject, 10 mg Tirzepatide=EXPERIMENTAL+subject, 15 mg Tirzepatide=EXPERIMENTAL+subject)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT03861052declared_contrast×12 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (5 mg Tirzepatide=EXPERIMENTAL+subject, 10 mg Tirzepatide=EXPERIMENTAL+subject, 15 mg Tirzepatide=EXPERIMENTAL+subject, 0.75 mg Dulaglutide=ACTIVE_COMPARATOR)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT03882970declared_contrast×9 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (10 mg Tirzepatide=EXPERIMENTAL+subject, 15 mg Tirzepatide=EXPERIMENTAL+subject, Insulin Degludec=ACTIVE_COMPARATOR)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT03951753declared_contrast×9 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (Tirzepatide 15 mg=EXPERIMENTAL+subject, Semaglutide 1 mg=ACTIVE_COMPARATOR, Placebo=PLACEBO_COMPARATOR)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT03954834declared_contrast×8, dose_stratum×1 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (5 mg Tirzepatide=EXPERIMENTAL+subject, 10 mg Tirzepatide=EXPERIMENTAL+subject, 15 mg Tirzepatide=EXPERIMENTAL+subject, Placebo=PLACEBO_COMPARATOR)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT03987919declared_contrast×10 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (10 mg Tirzepatide=EXPERIMENTAL+subject, 15 mg Tirzepatide=EXPERIMENTAL+subject, 1 mg Semaglutide=ACTIVE_COMPARATOR)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT04004988declared_contrast×2 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (5 mg Tirzepatide AI=unmatched, 5 mg Tirzepatide PFS=unmatched)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT04039503declared_contrast×11 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (10 mg Tirzepatide=EXPERIMENTAL+subject, 15 mg Tirzepatide=EXPERIMENTAL+subject, Placebo=PLACEBO_COMPARATOR)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT04050553declared_contrast×7 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (Placebo=PLACEBO_COMPARATOR, Tirzepatide 15 mg=unmatched)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT04050670declared_contrast×2 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (Tirzepatide - Abdomen=ACTIVE_COMPARATOR+subject, Tirzepatide - Upper Arm=EXPERIMENTAL+subject, Tirzepatide - Thigh=EXPERIMENTAL+subject)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT04081337declared_contrast×16 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (Placebo=PLACEBO_COMPARATOR, 15 mg Tirzepatide=unmatched)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT04093752declared_contrast×10 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (10 mg Tirzepatide=EXPERIMENTAL+subject, 15 mg Tirzepatide=EXPERIMENTAL+subject, Insulin Glargine=ACTIVE_COMPARATOR)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT04166773declared_contrast×4, dose_stratum×2 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (5 mg Tirzepatide=EXPERIMENTAL+subject, 10 mg Tirzepatide=EXPERIMENTAL+subject, 15 mg Tirzepatide=EXPERIMENTAL+subject, Placebo=PLACEBO_COMPARATOR)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT04184622declared_contrast×26 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (Placebo=PLACEBO_COMPARATOR, 5 mg Tirzepatide=EXPERIMENTAL+subject, 10 mg Tirzepatide=EXPERIMENTAL+subject, 15 mg Tirzepatide=EXPERIMENTAL+subject)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT04255433declared_contrast×14 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (Tirzepatide (MTD)=unmatched, 1.5 mg Dulaglutide=EXPERIMENTAL)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT04311411declared_contrast×1, multiple_analyses×1, stratified×1 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (Placebo=PLACEBO_COMPARATOR, Tirzepatide=EXPERIMENTAL+subject)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT04537923declared_contrast×10 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (Pooled 5 mg/10 mg/15 mg Tirzepatide=unmatched, Insulin Lispro=ACTIVE_COMPARATOR)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT04657003declared_contrast×26 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (Placebo=PLACEBO_COMPARATOR, 10 mg Tirzepatide=unmatched, 15 mg Tirzepatide=EXPERIMENTAL+subject)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT04657016declared_contrast×22 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (Placebo=PLACEBO_COMPARATOR, Tirzepatide=EXPERIMENTAL+subject)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT04660643declared_contrast×24, multiple_analyses×2 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (Placebo=PLACEBO_COMPARATOR, Tirzepatide MTD=EXPERIMENTAL+subject)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT04844918declared_contrast×24, outcome_node×2 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (10 mg Tirzepatide=unmatched, 15 mg Tirzepatide=EXPERIMENTAL+subject, Placebo=PLACEBO_COMPARATOR)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT04847557declared_contrast×11 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (Tirzepatide - MTD=unmatched, Placebo=PLACEBO_COMPARATOR)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT05024032declared_contrast×20, outcome_node×1 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (10 mg Tirzepatide=unmatched, 15 mg Tirzepatide=EXPERIMENTAL+subject, Placebo=PLACEBO_COMPARATOR)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT05260021declared_contrast×14 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (Pooled Doses of Tirzepatide (5 mg, 10 mg)=unmatched, Placebo=PLACEBO_COMPARATOR+subject)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT05412004declared_contrast×6, dose_stratum×2, commit×1 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (Tirzepatide MTD_GPI1=EXPERIMENTAL+subject, Placebo_GPI1=PLACEBO_COMPARATOR, Tirzepatide MTD_GPI2=EXPERIMENTAL+subject, Placebo_GPI2=PLACEBO_COMPARATOR)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT05564039declared_contrast×13 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (15 mg Tirzepatide or MTD=unmatched, 4.5 mg Dulaglutide or MTD=ACTIVE_COMPARATOR)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT05691712declared_contrast×16 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (10 mg Tirzepatide=EXPERIMENTAL+subject, 15 mg Tirzepatide=EXPERIMENTAL+subject, Placebo=PLACEBO_COMPARATOR)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT05696847declared_contrast×3 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (Cohort 1: Placebo (BW >=50 kg)=PLACEBO_COMPARATOR, Cohort 1: 2.5-5 mg Tirzepatide (BW >=50 kg)=EXPERIMENTAL+subject, Cohort 2: Placebo (BW <50 kg)=PLACEBO_COMPARATOR, Cohort 2: 1.25-2.5 mg Tirzepaclinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT05810597declared_contrast×3 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (Tirzepatide (SDP)=unmatched, Tirzepatide (MUPFP)=unmatched)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT05822830declared_contrast×9 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (15 mg or MTD - Tirzepatide=EXPERIMENTAL+subject, 2.4 mg or MTD - Semaglutide=ACTIVE_COMPARATOR)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT05963022declared_contrast×8, verify:object_plausibility×1, dose_stratum×1 — "Percentage of Participants Who Achieved Weight Loss of ≥10%" names CAT:outcome/serum-25-hydroxyvitamin-d ("Serum 25-hydroxyvitamin D concentration") at least as well as CAT:outcome/body-mass ("Body mass") — the span does not pick out the endpoint claimedclinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
NCT06533527declared_contrast×3 — no posted analysis compares a tirzepatide arm with a placebo/no-intervention arm and carries a p-value (Continue medication as normal prior to endoscopic procedure=ACTIVE_COMPARATOR+subject, Hold dose prior to endoscopic procedure=NO_INTERVENTION)clinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
PMID:41161687claims extracted but refused by the deterministic validatorspipeline:batch2026-10-05
NCT05978713design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=tirzepatide2026-09-29
PMID:40368575no claim extracted — instrument_not_stated — measured: metabolic syndrome presence under a criteria set the Methods describe only as 'based on the guidelines' without naming ATP III, IDF or the harmonised definitionpipeline:batch2026-10-05