Compound
pppGp(2'-5')A
An organophosphate oxoanion obtained by deprotonation of the phosphate and triphosphate OH groups of pppGp(2'→5')A; major species at pH 7.3.
Definition from ChEBI (CHEBI:78318), read 2026-09-23. CC BY 4.0.
CHEBI:78318ChEBI
Structure
No depiction stored
- Class
- Organic compound, anion
- Formula
- C20H23N10O20P4
- Mass
- 847.35 g/mol
- Charge
- -5
- InChIKey
- AAOPLQLDGHSOGE-INFSMZHSSA-I
- SMILES
- Nc1nc(=O)c2ncn([C@@H]3O[C@H](COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])[O-])[C@@H](O)[C@H]3OP(=O)([O-])OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](O)[C@@H]3O)c2n1
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Statements
3 statements
3 statements · 1 reference database · Subject: pppGp(2'-5')A · Sources: Rhea
- pppGp(2'-5')A is converted to 2',3'-cGAMPCompoundRhea RHEA:23924Inferred only
- 2',3'-cGAMP is converted to pppGp(2'-5')ACompoundRhea RHEA:23924Inferred only
- pppGp(2'-5')A is a substrate of CGASProteinRhea RHEA:23924Inferred only
Reactions
2 reactions
GTP+ATP(4-)pppGp(2'-5')A+diphosphate(3-)
Catalysed by CGAS
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:23748CC BY 4.0Reference data
pppGp(2'-5')A2',3'-cGAMP+diphosphate(3-)
Catalysed by CGAS
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:23924CC BY 4.0Reference data