Compound
losartan
No description recorded for this entry yet. Everything this graph holds about losartan is below.
Structure
- Class
- Organic compound, anion
- Formula
- C22H22ClN6O
- Mass
- 421.912 g/mol
- Charge
- -1
- InChIKey
- MDMTUGIZSFHDIC-UHFFFAOYSA-N
- SMILES
- CCCCc1nc(Cl)c(CO)n1Cc1ccc(-c2ccccc2-c2nnn[n-]2)cc1
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence — none of it carries a grade.
What it touches on the way
A finding says losartan moved an endpoint. This is the biology in between: the proteins and reactions it runs through to get there. It is where to look for the two things a list of findings cannot answer — why a result might happen, and what else acts on the same machinery.
4 of these are proteins with a page of their own, and that is the door: a protein page says what else it carries, which is how one compound leads to the next.
Mechanistic reach
4 entities
4 entities reached, most connected first. Hub metabolites are excluded, so this is not a claim that the compound touches everything.
0 reported hops4 assembled from the scaffold
What the reference databases state
The section above shows paths a projection assembled. This is the reference layer itself, one step from losartan: what the cleared databases state it reacts with, is carried by, is converted to and takes part in, whether or not a projection has walked it yet.
Regulatory determinations
Published numbers and scores, transcribed from the body that issued them. A determination is not a finding and is not graded; it is the number, who set it, and the document it came from.
LiverTox likelihood score CLiverTox
LiverTox Likelihood Score C — probably linked to idiosyncratic liver injury, reported uncommonly. Chapter: "Losartan". Source: LiverTox Master List (NBK571102).
The document·Public Domain (NLM/NIH)·Transcribed, not graded
Statements
4 statements
4 statements in 1 reference database name losartan — Rhea. Press a relation to see only its rows; every count is the rows behind it.
- losartan is metabolised by UGT1A1ProteinRhea RHEA:63720Inferred only
- losartan is metabolised by UGT1A10ProteinRhea RHEA:63720Inferred only
- losartan is metabolised by UGT1A3ProteinRhea RHEA:63720Inferred only
- losartan is metabolised by UGT2B7ProteinRhea RHEA:63720Inferred only
Other names
1 name
Every name this graph resolves to losartan. Searching any of them lands here.
- Systematic name
- 5-(4'-{[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl}[biphenyl]-2-yl)tetrazol-1-ide