Compound

CHEBI:37463

An ester formed between the aldehydic carbon of ribose and the terminal phosphate of adenosine diphosphate. It is produced by the hydrolysis of nicotinamide-adenine dinucleotide (NAD) by a variety of enzymes, some of which transfer an adp-ribosyl group to target proteins.

Definition from MeSH (D000246), National Library of Medicine, read 2026-09-23. NLM revises MeSH; this copy may not reflect its current record.

CHEBI:37463ChEBI

Open in the graph

Reactions

4 reactions

water+NADP(3-)CHEBI:37463+proton+nicotinamide
Catalysed by CD38 or BST1
Reaction pageLeft to rightBalancedEC 3.2.2.5GO:0005829
Human-GEM MAR07627CC BY 4.0Reference data
water+NADP(3-)CHEBI:37463+proton+nicotinamide
Catalysed by CD38
Reaction pageLeft to rightBalancedEC 3.2.2.5GO:0005615
Human-GEM MAR08788CC BY 4.0Reference data
CHEBI:37463
Reaction pageReversibleBalance undeterminableGO:0005615
Human-GEM MAR09256CC BY 4.0Reference data
CHEBI:37463CHEBI:37463
Reaction pageReversibleBalancedGO:0005829, GO:0005615
Human-GEM MAR09642CC BY 4.0Reference data

Other names

4 names

Resolves to: CHEBI:37463

Also called: Adenosine diphosphate riboseADP-ribose 2'-phosphateADPribose 2'-phosphate
Systematic name: 2'-phosphoadenosine 5'-[3-(D-ribofuranosyl) dihydrogen diphosphate]