capsaicin/Record

Papers screened

Screened: 529
Admitted: 1
Discarded: 126
Not read: 402

24 queries

"capsaicin"[ti] [rct]
"capsaicin"[ti] [meta_analysis]
"capsaicin"[ti] [systematic_review]
"capsaicin"[ti] [observational]
clinicaltrials.gov intr search: query.intr=capsaicin
cited by PMID:20395849 [mechanism]; about CHEBI:3374 by its own indexing
cited by PMID:20420526 [mechanism]; about CHEBI:3374 by its own indexing
cited by PMID:20420526 [cited]; about CHEBI:3374 by its own indexing
cited by PMID:20420526 [rct]; about CHEBI:3374 by its own indexing
cited by PMID:23033919 [mechanism]; about CHEBI:3374 by its own indexing
cited by PMID:23111102 [cited]; about CHEBI:3374 by its own indexing
cited by PMID:23111102 [mechanism]; about CHEBI:3374 by its own indexing
cited by PMID:23111102 [observational]; about CHEBI:3374 by its own indexing
cited by PMID:23806384 [mechanism]; about CHEBI:3374 by its own indexing
cited by PMID:26447990 [mechanism]; about CHEBI:3374 by its own indexing
cited by PMID:27023003 [mechanism]; about CHEBI:3374 by its own indexing
cited by PMID:28637424 [cited]; about CHEBI:3374 by its own indexing
cited by PMID:20936417 [cited]; about CHEBI:3374 by its own indexing
pipeline:batch
pipeline:batch (verification stage)
cited by PMID:19821411 [cited]; about CHEBI:3374 by its own indexing
cited by PMID:21203440; efetch/papersFor returned no usable record
cited by PMID:21203440; its own chemicals/MeSH/title name no enrolled subject
cited by PMID:21203440 [cited]; about CHEBI:3374 by its own indexing

Produced a finding1 paper

PMID:42816054"capsaicin"[ti] [meta_analysis]2026-10-25

Discarded — the wrong intervention70 papers

NCT00321672intervention×1 — no declared intervention names capsaicinclinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT00699556intervention×1 — no declared intervention names capsaicinclinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT01037816intervention×1 — no declared intervention names capsaicinclinicaltrials.gov intr search: query.intr=capsaicin

Back to capsaicin

Discarded — another reason, stated per paper24 papers

NCT00870896design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT00947284design×1 — allocation NON_RANDOMIZED -- not randomisedclinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT01260454design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT01575106design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT01854268design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT02183519design×1 — allocation NON_RANDOMIZED -- not randomisedclinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT02203162design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT02240329design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT02346903design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT02346916design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT02537951design×1 — allocation NON_RANDOMIZED -- not randomisedclinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT02766517design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT03122145design×1 — allocation NON_RANDOMIZED -- not randomisedclinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT03321019design×1 — studyType OBSERVATIONAL -- only INTERVENTIONAL is extractedclinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT03722849design×1 — allocation NON_RANDOMIZED -- not randomisedclinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT05093478design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT05265871design×1 — studyType OBSERVATIONAL -- only INTERVENTIONAL is extractedclinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
PMID:21203440no claim extracted — cause not determinedpipeline:batch2026-10-25
PMID:22038945no claim extracted — cause not determined (one pass only) — measured: whole-body energy expenditure and fat oxidation after capsaicin or capsiate, instrument not stated in abstract; orexigenic sensations, instrument not statedpipeline:batch2026-10-25
PMID:42237588no claim extracted — cause not determined (one pass only) — measured: pain score pre-post change after 8% capsaicin patch in HIV-associated distal sensory polyneuropathy, pooled standardised effect, instrument not namedpipeline:batch2026-10-25
PMID:33291700no claim extracted — cause not determined — DOSED: 2 g dried red chili powder (Capsicum frutescens Linn, 1.46 mg capsaicin per 2 g), Methods 2.2; a whole-plant spice, not purified capsaicin (one pass only) — measured: gastric accommodation, maximal postprandial gastric volume minus fasting gastric volume by SPECT with 99mTc-pertechnetatepipeline:batch2026-10-25
PMID:33374147no claim extracted — subject_absent — DOSED: Capsiate, a capsinoid ('capsaicin analogue'), 2 x 12 mg capsules from a capsicum extract/maltodextrin product, Methods 2.3; the paper does not dose capsaicin | capsiate (capsinoid, called a 'capsaicin analogue'; Capsicum annuum extract standardised to capsiate, 2 x 12 mg orally), Methods section 2.3; capsaicin itself was not givenpipeline:batch2026-10-25
PMID:34044838no claim extracted — cause not determinedpipeline:batch2026-10-25
PMID:39747887no claim extracted — cause not determined (one pass only) — measured: area of capsaicin-induced secondary pinprick hyperalgesia and allodynia, von Frey 180 g filament and brush mapping, ImageJ areapipeline:batch2026-10-25

Discarded — no extractable result17 papers

NCT00655811declared_contrast×3 — no posted analysis compares a capsaicin arm with a placebo/no-intervention arm and carries a p-value (African Americans=unmatched, Caucasians=unmatched, East Asians=unmatched, Hispanics=unmatched)clinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT00693160declared_contrast×2 — no posted analysis compares a capsaicin arm with a placebo/no-intervention arm and carries a p-value (Intrathecal Ketorolac=EXPERIMENTAL+subject, Placebo Intrathecal Injection=PLACEBO_COMPARATOR+subject)clinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT01231750declared_contrast×6, reporting_status×1 — no posted analysis compares a capsaicin arm with a placebo/no-intervention arm and carries a p-value (0.1% Capsaicin Cream First, Then Placebo=unmatched, Placebo First, Then 0.1% Capsaicin=unmatched)clinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT01533428multiple_analyses×7, declared_contrast×6, stratified×3, outcome_node×2 — 11 analyses of the same contrast (ANCOVA p=0.208; ANCOVA p=0.036; ANCOVA p=0.027; ANCOVA p=0.024; ANCOVA p=0.051; ANCOVA p=0.012; ANCOVA p=0.026; ANCOVA p=0.032; ANCOVA p=0.020; ANCOVA p=0.022; ANCOVA p=0.005) -- the record does not declare which is primaryclinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT02288156declared_contrast×6 — no posted analysis compares a capsaicin arm with a placebo/no-intervention arm and carries a p-value (0,1mM=ACTIVE_COMPARATOR+subject, 0,01mM=EXPERIMENTAL+subject, 0.001mM=EXPERIMENTAL+subject, Placebo=PLACEBO_COMPARATOR)clinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT02493257declared_contrast×4 — no posted analysis compares a capsaicin arm with a placebo/no-intervention arm and carries a p-value (Intranasal Capsaicin=EXPERIMENTAL+subject, Vehicle Solution=PLACEBO_COMPARATOR)clinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT02700815declared_contrast×8 — no posted analysis compares a capsaicin arm with a placebo/no-intervention arm and carries a p-value (Placebo Gel=unmatched, Capsaicin (0.075%) Gel=unmatched, Diclofenac (2%) Gel=unmatched, Diclofenac (2%) +Capsaicin (0.075%) Gel=unmatched)clinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT03661996declared_contrast×8 — no posted analysis compares a capsaicin arm with a placebo/no-intervention arm and carries a p-value (Group 1. Breg Cooling Control=unmatched, Group 2. Gel Pack Cooling=unmatched, Group 3. Shortened Gel Pack Cooling=unmatched, Group 4. Single Needle Injection Gel Pack Cooling - 2% Lidocaine=unmatcheclinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
NCT03794388declared_contrast×2 — no posted analysis compares a capsaicin arm with a placebo/no-intervention arm and carries a p-value (Arm CAPSAICINE Topical=EXPERIMENTAL+subject, Arm PREGABALINE=ACTIVE_COMPARATOR)clinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
PMID:30172837claims extracted but the two passes did not agreepipeline:batch2026-10-25
PMID:36364793claims extracted but refused by the deterministic validatorspipeline:batch2026-10-25
PMID:40781895claims extracted but the two passes did not agreepipeline:batch2026-10-25
PMID:41932827no claim extracted — quote_not_self_supportingpipeline:batch2026-10-25
PMID:42653103claims extracted but refused by the deterministic validatorspipeline:batch2026-10-25
PMID:33308274no claim extracted — no_quantitative_resultpipeline:batch2026-10-25
PMID:35057413claims extracted but refused by the deterministic validatorspipeline:batch2026-10-25
PMID:35351835claims extracted but the two passes did not agreepipeline:batch2026-10-25

Discarded — an endpoint this vocabulary does not hold6 papers

NCT05298202outcome_node×6 — "Skin Blood Flow" names no outcome in the closed vocabularyclinicaltrials.gov intr search: query.intr=capsaicin2026-10-12
PMID:15033881no claim extracted — no_outcome_node — measured: proportion achieving about 50% pain reduction in chronic neuropathic pain, pooled relative benefit and NNT | responder proportion with about 50% pain reduction in chronic neuropathic pain, relative benefit and NNT, pooled across inconsistent definitionspipeline:batch2026-10-25
PMID:19821411no claim extracted — no_outcome_node — measured: proportion achieving clinical improvement in neuropathic pain (at least 50% pain reduction or equivalent global or categorical measure), pooled relative benefit and NNT | responder proportion with clinical improvement in neuropathic pain, pooled across inconsistent definitions (at least 50%, 40%, 75% or categorical pain relief), number needed to treatpipeline:batch2026-10-25
PMID:30888737no claim extracted — endpoint_near_miss — measured: WOMAC pain with walking single item on a 0-10 numeric scale, AUC of change from baseline (not the 5-item WOMAC pain subscale); WOMAC stiffness 0-20 and function 0-170 numeric-rating versions | WOMAC pain with walking single item (QA1) 0-10 numerical scale as daily-diary AUC, not the 5-item WOMAC pain subscale; stiffness scored 0-20 and function 0-170 rather than the node's Likert 0-8 and 0-68 formatspipeline:batch2026-10-25
PMID:34215800no claim extracted — no_outcome_node — measured: motor unit recruitment order difference pre-post, surface EMG decomposition; motor unit action potential variance, intramuscular EMG; brush allodynia area (BAS) | motor unit recruitment order difference (post minus pre) by surface EMG decomposition, and motor unit action potential variance by intramuscular EMG template matchingpipeline:batch2026-10-25
PMID:38135109no claim extracted — no_outcome_node — measured: oral burn intensity rating on a general labeled magnitude scale (gLMS), capsaicin desensitization change score | oral burn intensity rating on a general labeled magnitude scale (gLMS 0-100), change score from visit 2 to visit 3pipeline:batch2026-10-25