Compound
8-iso-prostaglandin F2alpha
A prostaglandin carboxylic acid anion that is the conjugate base of 8-epi-prostaglandin F2α, obtained by deprotonation of the carboxy group. Major structure at pH 7.3.
Definition from ChEBI (CHEBI:77768), read 2026-09-23. CC BY 4.0.
CHEBI:77768ChEBI
Structure
- Class
- Organic compound, anion
- Formula
- C20H33O5
- Mass
- 353.479 g/mol
- Charge
- -1
- InChIKey
- PXGPLTODNUVGFL-NAPLMKITSA-M
- SMILES
- CCCCC[C@H](O)/C=C/[C@@H]1[C@H](C/C=CCCCC(=O)[O-])[C@@H](O)C[C@H]1O
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
3 entities
3 entities reached.
What the reference databases state
Chemical structure
- 8-iso-prostaglandin F2alpha-glucuronide has the functional parent 8-iso-prostaglandin F2alphaCompoundChEBI CHEBI:229786Inferred only
Statements
3 statements
3 statements · 1 reference database · Subject: 8-iso-prostaglandin F2alpha · Sources: Rhea
- 8-iso-prostaglandin F2alpha is metabolised by UGT1A1ProteinRhea RHEA:79907Inferred only
- 8-iso-prostaglandin F2alpha is metabolised by UGT1A9ProteinRhea RHEA:79907Inferred only
- 8-iso-prostaglandin F2alpha is metabolised by UGT2B7ProteinRhea RHEA:79907Inferred only
Reactions
1 reaction
8-iso-prostaglandin F2alpha+UDP-alpha-D-glucuronate8-iso-prostaglandin F2alpha-glucuronide+UDP+hydron
Catalysed by UGT1A9 or UGT2B7 or UGT1A1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:79907CC BY 4.0Reference data
Other names
2 names
Resolves to: 8-iso-prostaglandin F2alpha
- Systematic name
- (5Z,13E,15S)-9alpha,11alpha,15-trihydroxy-8beta-prosta-5,13-dien-1-oate(5Z,13E,15S)-9α,11α,15-trihydroxy-8β-prosta-5,13-dien-1-oate