What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Statements
2 statements
2 statements · 1 reference database · Subject: 20alpha-hydroxy-5alpha-pregnane-3-one · Sources: Human-GEM
- 20alpha-hydroxy-5alpha-pregnane-3-one is converted to 5alpha-pregnane-3,20-dioneCompoundHuman-GEM MAR10071Inferred only
- 20alpha-hydroxy-5alpha-pregnane-3-one is a substrate of AKR1C3ProteinHuman-GEM MAR10071Inferred only
Reactions
3 reactions
NADP(3-)+20alpha-hydroxy-5alpha-pregnane-3-one5alpha-pregnane-3,20-dione+proton+NADPH(4-)
Catalysed by AKR1C3
Reaction pageLeft to rightBalancedEC 1.1.1.-GO:0005829
Human-GEM MAR10071CC BY 4.0Reference data
5alpha-pregnane-3,20-dione+NADPH(4-)+hydron20alpha-hydroxy-5alpha-pregnane-3-one+NADP(3-)
Catalysed by AKR1C4 or AKR1C2 or AKR1C1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:84163CC BY 4.0Reference data
20alpha-hydroxy-5alpha-pregnane-3-one+NADPH(4-)+hydronCHEBI:81470+NADP(3-)
Catalysed by AKR1C4 or AKR1C2 or AKR1C1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:84187CC BY 4.0Reference data