Compound
candesartan
No description recorded for this entry yet. Everything this graph holds about candesartan is below.
Structure
- Class
- Organic compound, anion
- Formula
- C24H18N6O3
- Mass
- 438.447 g/mol
- Charge
- -2
- InChIKey
- BSLSLQSFLOCXQQ-UHFFFAOYSA-L
- SMILES
- CCOc1nc2cccc(C(=O)[O-])c2n1Cc1ccc(-c2ccccc2-c2nnn[n-]2)cc1
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence — none of it carries a grade.
What it touches on the way
A finding says candesartan moved an endpoint. This is the biology in between: the proteins and reactions it runs through to get there. It is where to look for the two things a list of findings cannot answer — why a result might happen, and what else acts on the same machinery.
6 of these are proteins with a page of their own, and that is the door: a protein page says what else it carries, which is how one compound leads to the next.
Mechanistic reach
6 entities
6 entities reached, most connected first. Hub metabolites are excluded, so this is not a claim that the compound touches everything.
0 reported hops6 assembled from the scaffold
- UGT2B7ProteinUNIPROT:P16662metabolized byInferred only32 paths16 endpoints
- UGT1A10ProteinUNIPROT:Q9HAW8metabolized byInferred only28 paths14 endpoints
- UGT1A9ProteinUNIPROT:O60656metabolized byInferred only24 paths24 endpoints
- UGT1A3ProteinUNIPROT:P35503metabolized byInferred only15 paths15 endpoints
- UGT1A7ProteinUNIPROT:Q9HAW7metabolized byInferred only12 paths12 endpoints
- UGT1A8ProteinUNIPROT:Q9HAW9metabolized byInferred only11 paths11 endpoints
What the reference databases state
The section above shows paths a projection assembled. This is the reference layer itself, one step from candesartan: what the cleared databases state it reacts with, is carried by, is converted to and takes part in, whether or not a projection has walked it yet.
Regulatory determinations
Published numbers and scores, transcribed from the body that issued them. A determination is not a finding and is not graded; it is the number, who set it, and the document it came from.
LiverTox likelihood score CLiverTox
LiverTox Likelihood Score C — probably linked to idiosyncratic liver injury, reported uncommonly. Chapter: "Candesartan". Source: LiverTox Master List (NBK571102).
The document·Public Domain (NLM/NIH)·Transcribed, not graded
Statements
8 statements
8 statements in 1 reference database name candesartan — Rhea. Press a relation to see only its rows; every count is the rows behind it.
- candesartan is metabolised by UGT1A10ProteinRhea RHEA:63728Inferred only
- candesartan is metabolised by UGT1A10ProteinRhea RHEA:63724Inferred only
- candesartan is metabolised by UGT1A3ProteinRhea RHEA:63728Inferred only
- candesartan is metabolised by UGT1A7ProteinRhea RHEA:63724Inferred only
- candesartan is metabolised by UGT1A8ProteinRhea RHEA:63724Inferred only
- candesartan is metabolised by UGT1A9ProteinRhea RHEA:63724Inferred only
- candesartan is metabolised by UGT2B7ProteinRhea RHEA:63728Inferred only
- candesartan is metabolised by UGT2B7ProteinRhea RHEA:63724Inferred only
Other names
1 name
Every name this graph resolves to candesartan. Searching any of them lands here.
- Systematic name
- 2-ethoxy-1-{[2'-(tetrazol-1-id-5-yl)[biphenyl]-4-yl]methyl}-1H-benzimidazole-7-carboxylate