Compound
SN-38
No description recorded for this entry yet. Everything this graph holds about SN-38 is below.
Structure
- Class
- Organic compound
- Formula
- C22H20N2O5
- Mass
- 392.411 g/mol
- Charge
- 0
- InChIKey
- FJHBVJOVLFPMQE-QFIPXVFZSA-N
- SMILES
- CCc1c2c(nc3ccc(O)cc13)-c1cc3c(c(=O)n1C2)COC(=O)[C@]3(O)CC
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence — none of it carries a grade.
What it touches on the way
A finding says SN-38 moved an endpoint. This is the biology in between: the proteins and reactions it runs through to get there. It is where to look for the two things a list of findings cannot answer — why a result might happen, and what else acts on the same machinery.
3 of these are proteins with a page of their own, and that is the door: a protein page says what else it carries, which is how one compound leads to the next.
Mechanistic reach
3 entities
3 entities reached, most connected first. Hub metabolites are excluded, so this is not a claim that the compound touches everything.
What the reference databases state
The section above shows paths a projection assembled. This is the reference layer itself, one step from SN-38: what the cleared databases state it reacts with, is carried by, is converted to and takes part in, whether or not a projection has walked it yet.
Statements
3 statements
3 statements in 1 reference database name SN-38 — Rhea. Press a relation to see only its rows; every count is the rows behind it.
- SN-38 is metabolised by UGT1A1ProteinRhea RHEA:63696Inferred only
- SN-38 is metabolised by UGT1A7ProteinRhea RHEA:63696Inferred only
- SN-38 is metabolised by UGT1A9ProteinRhea RHEA:63696Inferred only
Other names
8 names
Every name this graph resolves to SN-38. Searching any of them lands here.
- Also called
- 10-Hydroxy-7-ethylcamptothecin7-Ethyl-10-hydroxy-20(S)-camptothecin7-Ethyl-10-hydroxycamptothecinNK 012NK-012SN 38SN 38 lactone
- Systematic name
- (4S)-4,11-diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione